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Strifon Forte Dsc: Full Drug Profile

Medically reviewed by Min Clinic Staff | Updated: January 2026

Strifon Forte Dsc - General Information

A centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)

 

Pharmacology of Strifon Forte Dsc

Strifon Forte Dsc, a synthetic compound, inhibits antigen-induced bronchospasms and, hence, is used to treat asthma and allergic rhinitis. Strifon Forte Dsc is used as an ophthalmic solution to treat conjunctivitis and is taken orally to treat systemic mastocytosis and ulcerative colitis. Strifon Forte Dsc is also a centrally-acting agent for painful musculoskeletal conditions. Data available from animal experiments as well as human study indicate that chlorzoxazone acts primarily at the level of the spinal cord and subcortical areas of the brain where it inhibits multisynaptic reflex a.c. involved in producing and maintaining skeletal muscle spasm of varied etiology. The clinical result is a reduction of the skeletal muscle spasm with relief of pain and increased mobility of the involved muscles.

 

Strifon Forte Dsc for patients

 

Strifon Forte Dsc Interactions

The concomitant use of alcohol or other central nervous system depressants may have an additive effect.

 

Strifon Forte Dsc Contraindications

PARAFON FORTE DSC chlorzoxazone is contraindicated in patients with known intolerance to the drug.

 

Additional information about Strifon Forte Dsc

Strifon Forte Dsc Indication

For the relief of discomfort associated with acute painful musculoskeletal conditions.

Mechanism Of Action
Strifon Forte Dsc inhibits degranulation of mast cells, subsequently preventing the release of histamine and slow-reacting substance of anaphylaxis (SRS-A), mediators of type I allergic reactions. Strifon Forte Dsc also may reduce the release of inflammatory leukotrienes. Strifon Forte Dsc may act by inhibiting calcium influx.
Drug Interactions
Disulfiram Disulfiram increases chlorzoxazone levels
Food Interactions
Take without regard to meals.
Generic Name
Chlorzoxazone
Synonyms
Chloroxazone; Chlorzoxazon; Chlorzoxane
Drug Category
Muscle Relaxants, Central
Drug Type
Small Molecule; Approved
Other Brand Names containing Chlorzoxazone
Biomioran; EZE-DS; Escoflex; Flexazone; Mioran; Miotran; Myoflexin; Myoflexine; Neoflex; Paraflex; Parafon Forte Dsc; Pathorysin; Relaxazone; Remular; Remular-S; Solaxin; Strifon Forte Dsc; Usaf Ma-10;
Toxicity (Overdose)
Oral, mouse: LD50 = 440 mg/kg; Oral, rat: LD50 = 763 mg/kg; Symptoms of overdose include diarrhea, dizziness, drowsiness, headache, light-headedness, nausea, and vomiting.
Protein Binding
13-18%
Biotransformation
Chlorzoxazone is rapidly metabolized in the liver and is excreted in the urine, primarily in a conjugated form as the glucuronide.
Dosage Forms of Strifon Forte Dsc
Capsule Oral
Chemical IUPAC Name
5-chloro-3H-1,3-benzoxazol-2-one
Chemical Formula
C7H4ClNO2
Organisms Affected
Humans and other mammals